Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 4/20 | 0.40 |
| ▸ | ITK | Q08881 | 3/20 | 0.40 |
| ▸ | TGM2 | P21980 | 5/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548542 | 0.70 | BTK (0.49) | PTPN1PTPN11BTKMAPK3FGFR1 | |
| SCHEMBL28209518 | 0.70 | EGFR (0.39) | PTPN1PTPN11BTKITKTGM2 | |
| Sulfuric Acid SCHEMBL5244029 | 0.67 | MAPK3 (0.41) | PTPN1PTPN11ITKTGM2MAPK3 | |
| SCHEMBL28705303 | 0.65 | TGM2 (0.55) | PTPN1PTPN11BTKTGM2GSTO1 | |
| SCHEMBL613090 | 0.64 | TGM2 (0.65) | PTPN1PTPN11BTKTGM2GSTO1 | |
| SCHEMBL31228347 | 0.64 | TGM2 (0.65) | PTPN1PTPN11BTKTGM2GSTO1 | |
| SCHEMBL4452979 | 0.63 | TGM2 (0.46) | PTPN1PTPN11TGM2GSTO1F13A1 | |
| SCHEMBL9665615 | 0.63 | PTPN1 (0.65) | PTPN1PTPN11BTKTGM2GSTO1 | |
| SCHEMBL21808438 | 0.62 | TGM2 (0.44) | TGM2GSTO1TEKKDRF13A1 | |
| SCHEMBL30685458 | 0.62 | TGM2 (0.44) | TGM2GSTO1TEKKDRF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107854720-A | Medicine-carried polyhydroxylated polymer embolism microball with radiography function and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107854720-A | Medicine-carried polyhydroxylated polymer embolism microball with radiography function and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-03-30 | — | — | CN | disclosed |