Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 known ✓ | Q02750 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 16/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5537630 | 0.91 | MAPK3 (0.37) | MAPK3MAPK1EGFRITKF13A1 | |
| Sulfuric Acid SCHEMBL4461982 | 0.83 | MAPK3 (0.36) | MAPK3MAPK1EGFRITKMAP2K1 | |
| Sulfuric Acid SCHEMBL5242393 | 0.76 | TGM2 (0.37) | EGFRITKF13A1TGM2TGM1 | |
| Sulfuric Acid SCHEMBL5243123 | 0.74 | NPC1 (0.44) | EGFRITKF13A1TGM2TGM1 | |
| Sulfuric Acid SCHEMBL4456717 | 0.72 | JAK3 (0.33) | MAPK3MAPK1EGFR | |
| Sulfuric Acid SCHEMBL4458775 | 0.71 | EGFR (0.41) | EGFRTGM2 | |
| SCHEMBL28209518 | 0.70 | EGFR (0.39) | MAPK3EGFRITKF13A1TGM2 | |
| Pyrimidine SCHEMBL4456823 | 0.70 | BTK (0.36) | EGFRITKF13A1TGM2TGM1 | |
| SCHEMBL28564782 | 0.68 | TGM2 (0.52) | EGFRITKF13A1TGM2TGM1 | |
| SCHEMBL4452979 | 0.68 | TGM2 (0.46) | MAPK1EGFRF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828253-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | claimed |
| EP-1828255-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | claimed |
| WO-2006046254-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | claimed |
| US-20060094844-A1 | Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2006-05-04 | — | — | US | claimed |
| WO-2006046255-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | claimed |
| EP-1828253-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | disclosed |
| EP-1828255-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006046254-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006046255-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | disclosed |