Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8040237 | 1.00 | — | — | |
| Bicarbonate SCHEMBL8033775 | 0.94 | — | — | |
| Bicarbonate SCHEMBL541758 | 0.94 | CA4 (0.78) | — | |
| Bicarbonate SCHEMBL4160764 | 0.94 | — | — | |
| Bicarbonate SCHEMBL192950 | 0.94 | — | — | |
| Bicarbonate SCHEMBL242846 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1004788 | 0.89 | — | — | |
| Bicarbonate SCHEMBL9059393 | 0.89 | CA4 (0.70) | — | |
| Bicarbonate SCHEMBL10909603 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1004789 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952302-A | Muscarine M1 receptor forward direction allosteric modulators | 苏文生命科学有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-107924016-A | Single-side protective polarizing film, polarizing film with adhesive layer, and image display device | 日东电工株式会社 | 2018-04-17 | — | — | CN | disclosed |