Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839883 | 0.98 | HDAC1 (0.66) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL10971761 | 0.93 | HDAC1 (0.63) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL11253655 | 0.86 | SMN1; SMN2 (0.67) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3381304 | 0.85 | HDAC1 (0.70) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3379543 | 0.85 | HDAC1 (0.70) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL7387271 | 0.85 | HDAC1 (0.70) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3379592 | 0.85 | HDAC1 (0.70) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL5286879 | 0.85 | HDAC1 (0.70) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL12952426 | 0.84 | HDAC1 (0.68) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD | |
| SCHEMBL4953757 | 0.84 | HDAC1 (0.68) | HDAC1HDAC8SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099761-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-27 | — | — | EP | disclosed |
| US-20100063026-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | VILLAPHARMA RESEARCH S.L. (ES) | 2010-03-11 | — | — | US | disclosed |
| CN-101547906-A | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2009-09-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063026-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | NQO2, NDUFB5, NDUFB7 | HDAC1 1035/4885HDAC8 3440/4885SMN1; SMN2 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.