Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27925071 | 0.98 | LMNA (0.55) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL7684043 | 0.85 | ALDH1A1 (0.54) | LMNAALDH1A1TSHRHTTPOLB | |
| SCHEMBL6352533 | 0.79 | P2RX7 (0.61) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL2091467 | 0.77 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL3035928 | 0.77 | LMNA (0.62) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL6361740 | 0.75 | P2RX7 (0.65) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL950429 | 0.75 | ATM (0.44) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL4408444 | 0.74 | LMNA (0.59) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL2163180 | 0.74 | LMNA (0.59) | LMNAALDH1A1TSHRP2RX7KMT2A | |
| SCHEMBL156417 | 0.74 | ALDH1A1 (0.66) | LMNAALDH1A1TSHRP2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-A | 3 tetrazole radical benzene, 1,2 disulfonic acid amide derivative as metal beta lactamase restrainer | 默沙东公司 | 2018-04-17 | — | — | CN | disclosed |