Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613148 | 0.99 | PTAFR (0.34) | PTAFRTSHRBRD4CREBBPAKR1C3 | |
| SCHEMBL28210709 | 0.95 | PTAFR (0.33) | PTAFRBRD4CREBBPS1PR1 | |
| SCHEMBL27512767 | 0.95 | PTAFR (0.33) | PTAFRBRD4CREBBPKIF11 | |
| SCHEMBL28857412 | 0.88 | AKR1C3 (0.37) | PTAFRTSHRBRD4CREBBPAKR1C3 | |
| SCHEMBL28769778 | 0.87 | KIF11 (0.36) | AKR1C3AKR1C2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1238964 | 0.87 | RXRA (0.33) | PTAFRNPC1RAB9AALDH1A1PLA2G1B | |
| SCHEMBL4463931 | 0.86 | PTAFR (0.33) | PTAFRBRD4CREBBPKIF11DGAT1 | |
| SCHEMBL15163648 | 0.86 | — | — | |
| SCHEMBL4463470 | 0.84 | PTAFR (0.32) | PTAFRPARP1 | |
| SCHEMBL27670367 | 0.83 | KIF11 (0.33) | AKR1C3AKR1C2RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058350-B2 | Polypropylene composition | Basell Poliolefine Italia, s.r.l. (IT) | 2011-11-15 | — | — | US | claimed |
| CN-1222550-C | Semi-crystalline propylene polymer composition for producing biaxially stretched polypropylene films | BASELL POLYOLEFINE GMBH (DE) | 2005-10-12 | — | — | CN | claimed |
| CN-1423664-A | Semi-crystalline propylene polymer composition for producing biaxially stretched polypropylene films | BASELL POLYOLEFINE GMBH (DE) | 2003-06-11 | — | — | CN | claimed |
| EP-1252202-A1 | PARTLY CRYSTALLINE PROPYLENE POLYMERISATE COMPOSITION FOR PRODUCTION OF BIAXIAL-STRETCHED POLYPROPYLENE FILMS | Basell Polyolefine GmbH (DE) | 2002-10-30 | — | — | EP | claimed |
| WO-2001046274-A1 | PARTLY CRYSTALLINE PROPYLENE POLYMERISATE COMPOSITION FOR PRODUCTION OF BIAXIAL-STRETCHED POLYPROPYLENE FILMS | BASELL POLYOLEFINE GMBH (DE) | 2001-06-28 | — | — | WO | claimed |
| CN-114599661-B | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2024-03-12 | — | — | CN | disclosed |
| CN-111164111-B | Catalyst composition and method for preparing olefin polymer using the same | LG化学株式会社 | 2023-01-03 | — | — | CN | disclosed |
| CN-114599661-A | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2022-06-07 | — | — | CN | disclosed |
| CN-111164111-A | Catalyst composition and process for producing olefin polymer using the same | LG化学株式会社 | 2020-05-15 | — | — | CN | disclosed |
| CN-102264773-B | Method for transitioning between incompatible olefin polymerization catalyst systems | BASELL POLYOLEFINE GMBH | 2013-12-04 | — | — | CN | disclosed |
| CN-101688004-B | An irradiated polyolefin composition comprising a non - phenolic stabilizer | BASELL POLIOLEFINE SRL | 2013-11-20 | — | — | CN | disclosed |
| EP-1548023-B1 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| CN-1659200-A | High clarity flexible propylene copolymer compositions | BASELL POLYOLEFINE GMBH (DE) | 2005-08-24 | — | — | CN | disclosed |
| EP-1548037-A2 | Random propylene-ethylene copolymers | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1548022-A2 | Transition metal compound, ligand system, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1548023-A2 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| WO-2005030783-A1 | PROCESS FOR THE ISOMERIZATION OF METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-07 | — | — | WO | disclosed |
| WO-2004099225-A1 | PROCESS FOR THE PRODUCTION OF HALIDE METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2004-11-18 | — | — | WO | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | PTAFR 818/4885TSHR 3596/4885BRD4 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.