Eucatropine

Eucatropine

SCHEMBL28210942

CC1CC(OC(=O)C(O)c2ccccc2)CC(C)(C)N1C.CC1CC([O])CC(C)(C)N1C

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.91
LMNA P02545 5/20 0.89
NR1I2 O75469 1/20 0.60
ABCB11 O95342 1/20 0.60
CYP2C9 P11712 1/20 0.54
HSD17B10 Q99714 1/20 0.54
CHRM1 P11229 8/20 0.53
CHRM2 P08172 7/20 0.53
CHRM3 P20309 7/20 0.53
CHRM4 P08173 6/20 0.53
CHRM5 P08912 6/20 0.53
BLM P54132 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TSHR P16473 2/20 0.39
NFKB1 P19838 2/20 0.39
CYP1A2 P05177 1/20 0.39
HIF1A Q16665 1/20 0.39
HTR2C P28335 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eucatropine SCHEMBL132347 0.95 CYP2D6 (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Eucatropine SCHEMBL636552 0.94 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Cyclandelate SCHEMBL547043 0.75 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Cyclandelate SCHEMBL8060819 0.75 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Cyclandelate SCHEMBL5123 0.75 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Homatropine SCHEMBL28211528 0.72 LMNA (0.90) CYP2D6LMNANR1I2ABCB11CYP2C9
Homatropine SCHEMBL23468168 0.71 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Homatropine SCHEMBL9653008 0.71 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Homatropine SCHEMBL15275620 0.71 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9
Homatropine SCHEMBL23970 0.71 LMNA (1.00) CYP2D6LMNANR1I2ABCB11CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107884953-A Contact lenses and contact lens products 星欧光学股份有限公司 2018-04-06 CN disclosed