Cyclandelate

Cyclandelate

SCHEMBL547043

C[C@@H]1C[C@H](OC(=O)[C@@H](O)c2ccccc2)CC(C)(C)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 1.00
NR1I2 O75469 1/20 1.00
ABCB11 O95342 1/20 1.00
CYP2D6 P10635 3/20 0.65
CYP2C9 P11712 4/20 0.57
CYP3A4 P08684 2/20 0.57
ALDH1A1 P00352 2/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2C19 P33261 1/20 0.57
HSD17B10 Q99714 2/20 0.55
CHRM2 P08172 8/20 0.54
CHRM1 P11229 7/20 0.54
CHRM3 P20309 7/20 0.54
CHRM5 P08912 6/20 0.54
CHRM4 P08173 5/20 0.54
BLM P54132 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KMT2A Q03164 4/20 0.43
PABPC1 P11940 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclandelate SCHEMBL5123 1.00 LMNA (1.00) LMNANR1I2ABCB11CYP2D6CYP2C9
Cyclandelate SCHEMBL8060819 1.00 LMNA (1.00) LMNANR1I2ABCB11CYP2D6CYP2C9
Cyclandelate SCHEMBL9705893 0.86 LMNA (0.74) LMNANR1I2ABCB11CYP2D6CYP2C9
Cyclandelate SCHEMBL9705887 0.84 LMNA (0.70) LMNANR1I2ABCB11CYP2D6CYP2C9
Eucatropine SCHEMBL132347 0.79 CYP2D6 (1.00) LMNANR1I2ABCB11CYP2D6CYP2C9
SCHEMBL13894203 0.78 LMNA (0.71) LMNANR1I2ABCB11CYP2C9CYP3A4
Eucatropine SCHEMBL636552 0.78 LMNA (1.00) LMNANR1I2ABCB11CYP2D6CYP2C9
SCHEMBL6908933 0.77 ALDH1A1 (0.84) LMNANR1I2ABCB11CYP2D6CYP2C9
SCHEMBL3846512 0.77 ALDH1A1 (0.84) LMNANR1I2ABCB11CYP2D6CYP2C9
SCHEMBL3846508 0.77 ALDH1A1 (0.84) LMNANR1I2ABCB11CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011083188-A1 ROBOTISED DEVICE FOR INSPECTING PIPES FUNDACION CARTIF (ES) 2011-07-14 WO claimed
US-12595504-B2 Methods for screening compounds for bactericidal activity and for determining the sensitivity of bacterial samples CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2026-04-07 US disclosed
US-12227795-B2 Molecular programming tools PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-02-18 US disclosed
WO-2025012495-A1 APPARATUS, SYSTEM AND METHOD FOR MONITORING THE AGING AND/OR MACERATION PROCESSES OF AN ALCOHOLIC BEVERAGE IN A BARREL AND ALCOHOLIC BEVERAGE OBTAINED PRODUCTOS AGROVIN, S.A. (ES) 2025-01-16 WO disclosed
US-20240417804-A1 KIT, DEVICE AND METHOD FOR DISTINGUISHING BETWEEN OVARIAN CANCER AND BENIGN OVARIAN TUMORS TORAY INDUSTRIES, INC. (JP) 2024-12-19 US disclosed
US-20240310266-A1 BIOMARKERS FOR CANCER AND METHODS OF USE THEREOF NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2024-09-19 US disclosed
US-11933753-B2 Chemical sensing device QI DIAGNOSTICS LTD (CN) 2024-03-19 US disclosed
US-20230383282-A1 TYPE VI CRISPR ORTHOLOGS AND SYSTEMS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-11-30 US disclosed
US-11781151-B2 Insecticidal CRY1B variants having improved activity spectrum and uses thereof PIONEER HI-BRED INTERNATIONAL, INC. 2023-10-10 US disclosed
US-20230304065-A1 METHODS FOR SCREENING COMPOUNDS FOR BACTERICIDAL ACTIVITY AND FOR DETERMINING THE SENSITIVITY OF BACTERIAL SAMPLES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-09-28 US disclosed
US-4898856-A Method for treating central nervous system diseases AROONSAKUL CHAOVANEE (US) 1990-02-06 US disclosed
US-4897389-A Treating central nervous system diseases AROONSAKUL CHAOVANEE (US) 1990-01-30 US disclosed
EP-0324037-A1 Method of treatment of central nervous system diseases such as Alzheimer's disease and Parkinson's disease and method of diagnosing Alzheimer's disease Aroonsakul, Chaovanee (US) 1989-07-19 EP disclosed
US-4791099-A Method of treatment for central nervous system diseases such as Alzheimer's's disease AROONSAKUL CHAOVANEE (US) 1988-12-13 US disclosed
US-4778798-A Pharmaceutical compositions having vasodilating and antianoxic activities SEUREF A.G. (LI) 1988-10-18 US disclosed
US-4778798-A Pharmaceutical compositions having vasodilating and antianoxic activities SEUREF A.G. (LI) 1988-10-18 US disclosed
EP-0276543-A2 Use of buspirone for the improvement of short term memory Bristol-Myers Squibb Company (US) 1988-08-03 EP disclosed
EP-0276536-A2 Use of buspirone for the improvement of short term memory Bristol-Myers Squibb Company (US) 1988-08-03 EP disclosed
US-4687772-A Method for improvement of short term memory BRISTOL-MYERS COMPANY (US) 1987-08-18 US disclosed
EP-0228036-A2 Method for producing selected polypeptides in virally infected insect cells and polypeptides isolated therefrom Microgenesys, Inc. (US) 1987-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240310266-A1 BIOMARKERS FOR CANCER AND METHODS OF USE THEREOF PDCD1, PDCD1LG2, CD274 LMNA 4013/4885NR1I2 4295/4885ABCB11 4686/4885
US-12595504-B2 Methods for screening compounds for bactericidal activity and for determining the sensitivity of bacterial samples MRPL21, PGLS, CLPP LMNA 1978/4885NR1I2 3197/4885ABCB11 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.