SCHEMBL28211013

SCHEMBL28211013

C=CC(=O)Oc1ccccn1.C=CC(=O)Oc1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.41
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
LMNA P02545 2/20 0.38
P4HTM Q9NXG6 2/20 0.38
NAPRT Q6XQN6 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
THRA P10827 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CCR1 P32246 1/20 0.37
CCR5 P51681 1/20 0.37
CCR8 P51685 1/20 0.37
METAP1 P53582 1/20 0.37
BLM P54132 1/20 0.37
HIF1A Q16665 1/20 0.37
DOHH Q9BU89 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1056117 1.00 THRB (0.41) THRBCES2CES1LMNAP4HTM
Hydrochloric Acid SCHEMBL27744049 0.98 THRB (0.40) THRBCES2CES1LMNAP4HTM
Ethylene SCHEMBL10448321 0.98 THRB (0.40) THRBCES2CES1LMNAP4HTM
SCHEMBL28729509 0.98 THRB (0.40) THRBCES2CES1LMNAP4HTM
SCHEMBL7159690 0.85 KDM4E (0.43) CES2CES1LMNAP4HTMNAPRT
SCHEMBL29477732 0.83 CES2 (0.41) CES2CES1LMNAP4HTMNAPRT
SCHEMBL6245077 0.81 ALDH1A1 (0.41) CES2CES1LMNAP4HTMNAPRT
SCHEMBL5081081 0.79 CES2 (0.37) CES2CES1LMNAP4HTMNAPRT
SCHEMBL27297078 0.79 HCAR2 (0.46) CES2CES1LMNAP4HTMNAPRT
SCHEMBL6243649 0.79 CES2 (0.43) CES2CES1LMNAP4HTMNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105906555-B The method that one kind prepares 2,2 '-bipyridyl -4,4 '-diacrylate 河南省商业科学研究所有限责任公司 2018-04-24 CN disclosed
CN-105906555-B The method that one kind prepares 2,2 '-bipyridyl -4,4 '-diacrylate 河南省商业科学研究所有限责任公司 2018-04-24 CN disclosed