Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27297078 | 0.93 | HCAR2 (0.46) | KDM4EMAPTHPGDHSD17B10CES2 | |
| SCHEMBL29477732 | 0.86 | CES2 (0.41) | KDM4EMAPTCES2CES1LMNA | |
| SCHEMBL20267155 | 0.85 | TSHR (0.39) | KDM4EMAPTCES2CES1LMNA | |
| SCHEMBL20267153 | 0.85 | TSHR (0.39) | KDM4EMAPTCES2CES1LMNA | |
| SCHEMBL6245077 | 0.85 | ALDH1A1 (0.41) | KDM4EMAPTCES2CES1LMNA | |
| SCHEMBL28211013 | 0.85 | THRB (0.41) | KDM4ECES2CES1LMNAKMT2A | |
| SCHEMBL1056117 | 0.85 | THRB (0.41) | KDM4ECES2CES1LMNAKMT2A | |
| Ethylene SCHEMBL10448321 | 0.83 | THRB (0.40) | KDM4ECES2CES1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL27744049 | 0.83 | THRB (0.40) | KDM4ECES2CES1LMNAKMT2A | |
| SCHEMBL28729509 | 0.83 | THRB (0.40) | KDM4ECES2CES1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341527-A1 | PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX | ALTANA Pharma AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045693-A1 | PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX | ALTANA PHARMA AG (DE) | 2002-06-13 | — | — | WO | disclosed |
| EP-1001780-A1 | USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING MANIA | MERCK SHARP & DOHME LTD. (GB) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007376-A1 | USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING MANIA | MERCK SHARP & DOHME LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |