Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211313 | 0.83 | FKBP1A (0.71) | FKBP1AGLAKMT2APOLBCA1 | |
| SCHEMBL4710815 | 0.83 | HTR6 (0.51) | FKBP1AGLAKMT2APOLBCA1 | |
| SCHEMBL654548 | 0.74 | MAPT (1.00) | MAPTUSP2KMT2APOLBIKBKB | |
| Hydrochloric Acid SCHEMBL3253197 | 0.72 | MAPT (0.96) | MAPTUSP2KMT2APOLBIKBKB | |
| SCHEMBL5304087 | 0.72 | MAPT (0.87) | MAPTUSP2KMT2APOLBIKBKB | |
| SCHEMBL28211335 | 0.72 | RYR2 (0.50) | KMT2APOLB | |
| SCHEMBL29978636 | 0.72 | KMT2A (0.48) | FKBP1AUSP2GLAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL28210781 | 0.71 | RYR2 (0.49) | MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28210785 | 0.71 | KMT2A (0.47) | FKBP1AUSP2GLAKMT2APOLB | |
| SCHEMBL3894981 | 0.70 | L3MBTL1 (0.67) | MAPTUSP2KMT2AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |