Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210975 | 0.82 | NPY5R (0.50) | NPY5RSCN10AADORA2AKCNH2 | |
| SCHEMBL19514104 | 0.77 | KDM4E (0.55) | SCN5AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL28209158 | 0.77 | KIF11 (0.50) | NPC1NPY5RNISCHSCN2A | |
| SCHEMBL220155 | 0.77 | NPC1 (0.50) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1259204 | 0.74 | SCN5A (0.50) | SCN5AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL3458918 | 0.74 | NPY5R (0.47) | NPC1ALDH1A1MAPTRAB9ANPY5R | |
| SCHEMBL1259407 | 0.72 | SCN5A (0.49) | SCN5AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL21412311 | 0.72 | HDAC4 (0.40) | MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16835869 | 0.72 | SCN5A (0.49) | SCN5AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL13458062 | 0.71 | GABRA1 (0.52) | KDM4ENPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061974-B | Maleimide derivatives as the conditioning agent of WNT approach | 新加坡科技研究局 | 2018-04-20 | — | — | CN | disclosed |