SCHEMBL28212988

SCHEMBL28212988

NCCCCC(N)C(=O)C(Cl)S(=O)(=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.44
DPP8 Q6V1X1 2/20 0.44
DPP9 Q86TI2 1/20 0.44
GSR P00390 1/20 0.44
MMP2 P08253 2/20 0.43
MMP9 P14780 1/20 0.43
CA2 P00918 1/20 0.40
LTA4H P09960 1/20 0.39
THRB P10828 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP1 P03956 3/20 0.36
MMP7 P09237 3/20 0.36
MMP12 P39900 3/20 0.36
MMP13 P45452 3/20 0.36
ACE P12821 2/20 0.36
RNPEP Q9H4A4 1/20 0.36
LARS1 Q9P2J5 1/20 0.35
TERT O14746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200246 0.86 CA2 (0.41) DPP7DPP8DPP9GSRMMP2
Lysine SCHEMBL16553019 0.75 GSR (0.61) DPP7DPP8DPP9GSRMMP2
Lysine SCHEMBL16553020 0.75 GSR (0.61) DPP7DPP8DPP9GSRMMP2
SCHEMBL16553021 0.73 DPP8 (0.45) DPP7DPP8DPP9GSRMMP2
SCHEMBL9753072 0.73 LARS1 (0.62) DPP7DPP8DPP9GSRMMP2
SCHEMBL927264 0.70 ALPI (0.46) MMP9CA2LTA4HKMT2AMMP1
Anthraquinone SCHEMBL8876801 0.70 GSR (0.67) DPP7DPP8DPP9GSRMMP2
SCHEMBL27916184 0.69 SMN1; SMN2 (0.44) MMP2MMP9CA2TDP1MMP1
SCHEMBL28992842 0.69 GSR (0.55) DPP7DPP8DPP9GSRMMP2
SCHEMBL9631019 0.69 GSR (0.55) DPP7DPP8DPP9GSRMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107847713-A Eustachian tube dilation balloon with ventilation pathway 阿克拉伦特公司 2018-03-27 CN disclosed