SCHEMBL200246

SCHEMBL200246

Cc1ccc(S(=O)(=O)C(Cl)C(=O)[C@@H](N)CCCCN)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.41
GSR P00390 1/20 0.38
CA1 P00915 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 4/20 0.38
LMNA P02545 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
RAB9A P51151 1/20 0.35
THRB P10828 1/20 0.35
G6PD P11413 1/20 0.35
GBA1 P04062 1/20 0.35
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28212988 0.86 DPP7 (0.44) CA2GSRDPP8DPP9DPP7
SCHEMBL284483 0.82 CA2 (0.38) CA2GSRCA1ALDH1A1LMNA
SCHEMBL27752816 0.82 MMP9 (0.38) CA2CA1CA12CA9ALDH1A1
SCHEMBL31643134 0.78 GSR (0.42) CA2GSRCA1CA12CA9
SCHEMBL927264 0.76 ALPI (0.46) CA2CA1CA12CA9LMNA
SCHEMBL7871559 0.76 G6PD (0.41) CA2CA1CA12CA9ALDH1A1
SCHEMBL7202970 0.76 G6PD (0.41) CA2CA1CA12CA9ALDH1A1
SCHEMBL7202961 0.76 G6PD (0.41) CA2CA1CA12CA9ALDH1A1
Lysine SCHEMBL30145617 0.76 GSR (0.56) GSRMMP2MMP9THRBSLC1A3
Lysine SCHEMBL6683158 0.76 GSR (0.56) GSRMMP2MMP9THRBSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7914542-B2 Devices, systems and methods for treating benign prostatic hyperplasia and other conditions NEOTRACT, INC. (US) 2011-03-29 US claimed
US-20090192439-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2009-07-30 US claimed
US-20090060977-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2009-03-05 US claimed
US-20090018523-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2009-01-15 US claimed
EP-1887976-A2 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS Neotract, Inc. (US) 2008-02-20 EP claimed
US-20060276871-A1 Devices, systems and methods for treating benign prostatic hyperplasia and other conditions EXPLORAMED NC2, INC. (US) 2006-12-07 US claimed
WO-2006127431-A2 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2006-11-30 WO claimed
US-12268797-B2 Non-cultured, partially digested, cryopreserved cartilage product OSIRIS THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-12201283-B2 Devices, systems and methods for treating benign prostatic hyperplasia and other conditions Teleflex Life Sciences Llc (US) 2025-01-21 US disclosed
US-20240216180-A1 SYSTEM AND METHOD FOR TREATMENT OF EUSTACHIAN TUBE FROM MIDDLE EAR APPROACH ACCLARENT, INC. 2024-07-04 US disclosed
US-11944518-B2 System and method for treatment of eustachian tube from middle ear approach ACCLARENT, INC. (US) 2024-04-02 US disclosed
US-20240099892-A1 EUSTACHIAN TUBE DILATION BALLOON WITH VENTILATION PATH ACCLARENT, INC. 2024-03-28 US disclosed
US-11864725-B2 Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat ACCLARENT, INC. (US) 2024-01-09 US disclosed
US-20060106361-A1 Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders ACCLARENT, INC. (US) 2006-05-18 US disclosed
US-20060095066-A1 Devices, systems and methods for treating disorders of the ear, nose and throat EXPLORAMED NC1, INC. (US) 2006-05-04 US disclosed
WO-2006020180-A2 IMPLANTABLE DEVICES AND METHODS FOR DELIVERING DRUGS AND OTHER SUBSTANCES TO TREAT SINUSITIS AND OTHER DISORDERS ACCLARENT, INC. (US) 2006-02-23 WO disclosed
WO-2005117755-A2 DEVICES, SYSTEMS AND METHODS FOR TREATING SINUSITIUS ACCLARRENT, INC. (US) 2005-12-15 WO disclosed
US-20050245906-A1 Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders EXPLORAMED NC1, INC. (US) 2005-11-03 US disclosed
US-20050240147-A1 Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat EXPLORAMED II, INC. (US) 2005-10-27 US disclosed
US-5578477-A SCREENING FOR ANTICANCER DRUGS, SOURCE OF PURE ENZYME ARCH DEVELOPMENT CORPORATION (US) 1996-11-26 US disclosed