Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668390 | 0.82 | ACHE (0.36) | ALDH1A1 | |
| SCHEMBL5220727 | 0.81 | CYP11B1 (0.38) | CHRNA7KCNH2ALDH1A1CYP1A2ALOX15 | |
| Bromide SCHEMBL4482662 | 0.80 | CYP11B1 (0.37) | CHRNA7KCNH2ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL2820263 | 0.79 | SLC6A2 (0.31) | — | |
| SCHEMBL2677748 | 0.78 | CYP11B1 (0.39) | CHRNA7KCNH2ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL2823249 | 0.78 | ALDH1A1 (0.39) | PBRM1ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL2823335 | 0.78 | SLC6A2 (0.30) | — | |
| SCHEMBL2819737 | 0.77 | SCD (0.35) | — | |
| Hydrochloric Acid SCHEMBL2819670 | 0.77 | ALDH1A1 (0.38) | PBRM1ALDH1A1HSD17B10 | |
| SCHEMBL2819424 | 0.77 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922320-B1 | DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2010-10-27 | — | — | EP | claimed |