Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2819670 | 0.99 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTGAASMARCA2 | |
| SCHEMBL5217419 | 0.81 | CYP11B1 (0.38) | ALDH1A1KDM4EMAPTGAASMARCA2 | |
| Bromide SCHEMBL4472191 | 0.80 | CYP11B1 (0.37) | ALDH1A1KDM4EMAPTGAASMARCA2 | |
| SCHEMBL668390 | 0.79 | ACHE (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4442686 | 0.78 | CYP11B1 (0.39) | ALDH1A1KDM4EMAPTGAASMARCA2 | |
| SCHEMBL2821301 | 0.78 | CHRNA7 (0.35) | ALDH1A1PBRM1HSD17B10 | |
| SCHEMBL2820232 | 0.73 | — | — | |
| SCHEMBL2820263 | 0.73 | SLC6A2 (0.31) | — | |
| SCHEMBL2819756 | 0.73 | CHRM2 (0.33) | ALDH1A1MAPTKMT2ANPC1HSD17B10 | |
| SCHEMBL2846380 | 0.73 | IL4I1 (0.38) | KDM4EMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922320-B1 | DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2010-10-27 | — | — | EP | claimed |