SCHEMBL282143

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10127000	0.85	TDP1 (0.45)	CYP3A4TDP1ALOX15TP53THRB
	SCHEMBL14464889	0.80	ALDH1A1 (0.45)	TDP1SMN1; SMN2ALDH1A1KDM4ETSHR
	SCHEMBL2822609	0.79	CYP3A4 (0.43)	CYP3A4TDP1ALOX15TP53THRB
	SCHEMBL20085642	0.79	ALDH1A1 (0.42)	TP53SMN1; SMN2ALDH1A1KDM4ENPC1
	SCHEMBL30908409	0.78	CYP3A4 (0.50)	CYP3A4TDP1ALOX15TP53THRB
	SCHEMBL1522533	0.78	ALDH1A1 (0.59)	CYP3A4TDP1ALOX15TP53THRB
	SCHEMBL20150187	0.78	CYP3A4 (0.50)	CYP3A4TDP1ALOX15TP53THRB
	SCHEMBL23084394	0.77	CYP3A4 (0.54)	CYP3A4TDP1ALOX15TP53THRB
	SCHEMBL25519494	0.77	EDNRB (0.37)	CYP3A4ALDH1A1KDM4ETSHRNPC1
	SCHEMBL14866325	0.77	ALDH1A1 (0.46)	CYP3A4TDP1THRBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.