Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229856 | 0.86 | TAS1R3 (0.56) | HPGDGPR139P2RX7SIGMAR1LMNA | |
| SCHEMBL19302643 | 0.86 | HPGD (0.61) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL10613937 | 0.84 | HPGD (0.59) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL4148749 | 0.81 | HPGD (0.70) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL31028439 | 0.80 | HPGD (0.55) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL10605231 | 0.79 | POLB (0.64) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL8815153 | 0.79 | GAA (0.59) | HPGDPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL10792384 | 0.79 | HPGD (0.81) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL47348 | 0.78 | POLB (0.62) | HPGDCYP1A2POLBNPC1RAB9A | |
| SCHEMBL11146717 | 0.78 | HPGD (0.67) | HPGDCYP1A2POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461705-B | Dibenzazepine Zhuo diketone anti-tumor compounds and preparation method thereof | 中国医科大学 | 2018-04-10 | — | — | CN | disclosed |