Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214367 | 0.86 | HPGD (0.61) | P2RX7SIGMAR1GPR139HPGDLMNA | |
| SCHEMBL4158170 | 0.83 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL9491955 | 0.81 | TAS1R3 (0.57) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL5529489 | 0.80 | HPGD (0.62) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL11570780 | 0.79 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL6292861 | 0.78 | P2RX7 (0.57) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL6292862 | 0.78 | TMEM97 (0.58) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL8743573 | 0.78 | GPR139 (0.60) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL4143751 | 0.77 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 | |
| SCHEMBL4384455 | 0.77 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2P2RX7TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011090940-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2011-07-28 | — | — | WO | disclosed |