Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383965 | 0.80 | — | — | |
| SCHEMBL16501026 | 0.78 | TSHR (0.42) | KDM4E | |
| SCHEMBL11999780 | 0.76 | LDHA (0.38) | LDHASRRKDM4E | |
| SCHEMBL27645945 | 0.74 | — | — | |
| SCHEMBL15086383 | 0.74 | — | — | |
| SCHEMBL28911837 | 0.73 | LDHA (0.40) | LDHASRRKDM4EKDM6BKDM5C | |
| SCHEMBL19697941 | 0.71 | OR51E2 (0.42) | EGLN1 | |
| SCHEMBL5392230 | 0.71 | ALDH1A1 (0.48) | LDHASRRKDM4EKDM6BKDM5C | |
| SCHEMBL2285951 | 0.71 | — | — | |
| SCHEMBL6326748 | 0.71 | LTA4H (0.38) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483602-A | A kind of preparation method of Rui Jiadesong | CHANGZHOU FANG YUAN PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-110078747-A | A kind of novel thiazole class drug molecule and preparation method thereof for hospital disinfection | 河南科技大学第一附属医院 | 2019-08-02 | — | — | CN | claimed |
| CN-110483602-A | A kind of preparation method of Rui Jiadesong | CHANGZHOU FANG YUAN PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-110483602-A | A kind of preparation method of Rui Jiadesong | CHANGZHOU FANG YUAN PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-110214136-A | Pyrazole derivatives as MALT1 inhibitor | 詹森药业有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-110088099-A | AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF | EPIZYME股份有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110078747-A | A kind of novel thiazole class drug molecule and preparation method thereof for hospital disinfection | 河南科技大学第一附属医院 | 2019-08-02 | — | — | CN | disclosed |
| CN-105968156-B | A kind of αisomer impurity of Rui Jianuosheng and its preparation method and application | 南京海融医药科技股份有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-109153651-A | amido-substituted cyclohexane derivatives | 拜耳制药股份公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108586464-A | A kind of synthetic method of 3- bromines pyrazolo [1,5- α] pyrimidine -6- formic acid | 苏州康润医药有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-107903251-A | Pyrazole formylamine derivate as the TAAR conditioning agents for treating several conditions such as depression, diabetes and Parkinson's | 霍夫曼-拉罗奇有限公司 | 2018-04-13 | — | — | CN | disclosed |