SCHEMBL28215573

SCHEMBL28215573

Cc1ccc(C(C)C)c(N[C]=S)c1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
LMNA P02545 1/20 0.47
CHRM1 P11229 1/20 0.47
SLC6A2 P23975 1/20 0.47
ADRA1A P35348 1/20 0.47
HTR2B P41595 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11638202 0.79 TRPA1 (0.54) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL28841644 0.79 LMNA (0.40) LMNA
SCHEMBL1758595 0.78 RAPGEF4 (0.48) LMNA
SCHEMBL28192927 0.76 TRPA1 (0.50) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL28214670 0.76 TRPA1 (0.50) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL10406585 0.74 RAPGEF4 (0.50) LMNA
SCHEMBL4739123 0.74 L3MBTL1 (0.50) LMNASLC6A2HTR2B
SCHEMBL30186736 0.73 KDM4E (0.47) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL14576826 0.73 KDM4E (0.47) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL17454704 0.72 LMNA (0.46) TRPA1LMNACHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108025189-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2021-07-02 CN disclosed
CN-108025189-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 美国陶氏益农公司 2018-05-11 CN disclosed