SCHEMBL28215980

SCHEMBL28215980

Cc1cccn1-c1ccc(Cl)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.43
HSD11B1 P28845 3/20 0.42
PTPN1 P18031 1/20 0.40
GABRA2 P47869 4/20 0.39
GABRB2 P47870 4/20 0.39
LMNA P02545 1/20 0.38
HCAR1 Q9BXC0 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CDK2 P24941 1/20 0.37
GSK3B P49841 1/20 0.37
CYP11B2 P19099 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4540024 0.73 POLB (0.53) NOTUMGABRA2GABRB2LMNASMN1; SMN2
SCHEMBL8140296 0.72 NOTUM (0.47) NOTUMALDH1A1POLBGAANPSR1
SCHEMBL1613837 0.72 PKM (0.54) SMN1; SMN2HSD17B10ALDH1A1GAANPSR1
SCHEMBL3200156 0.71 KDM4E (0.48) NOTUMGABRA2GABRB2LMNASMN1; SMN2
SCHEMBL4716198 0.70 TP53 (0.44) LMNAHSD17B10L3MBTL1TSHRNPSR1
SCHEMBL27564981 0.69 GABRA2 (0.48) HSD11B1GABRA2GABRB2LMNAHCAR1
SCHEMBL8139682 0.68 NOTUM (0.44) NOTUMLMNASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL2543774 0.67 NOTUM (0.61) NOTUMGABRA2GABRB2LMNASMN1; SMN2
SCHEMBL3298524 0.67 KDM4E (0.46) NOTUMGABRA2GABRB2LMNAHCAR1
SCHEMBL27541379 0.67 DBH (0.51) LMNASMN1; SMN2ALDH1A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109329286-B Binary Herbicidal combinations and its application comprising HPPD inhibitor class herbicide 青岛清原化合物有限公司 2019-11-08 CN disclosed
CN-109964943-A Herbicidal combinations and its application comprising pyrimidine formoxyl oxime compound 江苏清原农冠杂草防治有限公司 2019-07-05 CN disclosed
CN-109526973-A Ternary weeding composition containing xaflufen-ethyl and application thereof 青岛清原化合物有限公司 2019-03-29 CN disclosed
CN-109497075-A Ternary weeding composition and its application comprising trifludimoxazin 青岛清原化合物有限公司 2019-03-22 CN disclosed
CN-109479888-A Ternary weeding composition and its application comprising cyclopyrimorate 青岛清原化合物有限公司 2019-03-19 CN disclosed
CN-109418274-A A kind of ternary weeding composition and its application 青岛清原化合物有限公司 2019-03-05 CN disclosed
CN-109392940-A Ternary Herbicidal combination comprising two kinds of sulfonylureas 拜耳作物科学股份公司 2019-03-01 CN disclosed
CN-109362763-A Ternary Herbicidal combination comprising two kinds of sulfonylureas 拜耳作物科学股份公司 2019-02-22 CN disclosed
CN-109329286-A Binary Herbicidal combinations and its application comprising HPPD inhibitor class herbicide 青岛清原化合物有限公司 2019-02-15 CN disclosed
CN-109042675-A Ternary herbicidal composition containing HPPD inhibitor herbicide and application thereof 青岛清原化合物有限公司 2018-12-21 CN disclosed
CN-105472983-B Ternary herbicide combinations comprising two sulfonylureas 拜耳作物科学股份公司 2018-11-13 CN disclosed
CN-108703144-A A kind of ternary weeding composition containing ring pyrrole fluorine humulone and its application 青岛清原化合物有限公司 2018-10-26 CN disclosed
CN-108552186-A Use of phenylpyrazoline-3-carboxylates for increasing plant yield 拜耳知识产权有限责任公司 2018-09-21 CN disclosed
CN-107897194-A Use of 5-phenyl-or 5-benzyl-2-isoxazoline-3-carboxylic acid esters for improving plant yield 拜耳知识产权有限责任公司 2018-04-13 CN disclosed