Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15209864 | 0.90 | PDE10A (0.47) | PDE10AMAPTNPY5RHTTSLC9A1 | |
| SCHEMBL15218575 | 0.85 | NPY5R (0.50) | MAPTNPY5RHTTSLC9A1KMT2A | |
| SCHEMBL28216149 | 0.83 | KMT2A (0.52) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL20028705 | 0.83 | ALDH1A1 (0.46) | PDE10AMAPTHTTSLC9A1ELANE | |
| SCHEMBL15209818 | 0.82 | PDE10A (0.42) | PDE10AMAPTNPY5RHTTSLC9A1 | |
| SCHEMBL15230495 | 0.81 | PDE10A (0.41) | PDE10AMAPTNPY5RHTTSLC9A1 | |
| SCHEMBL20027743 | 0.79 | KMT2A (0.48) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6314486 | 0.78 | SLC9A1 (0.65) | MAPTSLC9A1ELANEALDH1A1RAB9A | |
| SCHEMBL15218573 | 0.77 | LMNA (0.55) | MAPTNPY5RSLC9A1KMT2AMEN1 | |
| SCHEMBL20265483 | 0.76 | SLC9A1 (0.54) | MAPTSLC9A1ELANEALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596163-B2 | Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides | CHEMOCENTRYX, INC. (US) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596163-B2 | Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides | CCR9, CCR1, CCR3 | PDE10A 1218/4885MAPT 4727/4885NPY5R 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.