Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215793 | 0.85 | ROCK2 (0.46) | SMN1; SMN2ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL30024984 | 0.82 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL28215711 | 0.80 | HPGD (0.54) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL18425032 | 0.76 | VEGFA (0.48) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL28849642 | 0.74 | SIGMAR1 (0.61) | ALDH1A1KDM4EPOLBMAPTHRH3 | |
| Hydrochloric Acid SCHEMBL9840237 | 0.74 | SMN1; SMN2 (0.66) | HPGDSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL27824981 | 0.72 | LMNA (0.66) | LMNAALDH1A1POLBCA2HRH3 | |
| SCHEMBL28216456 | 0.72 | DRD4 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL31122730 | 0.71 | KMT2A (0.57) | HPGDLMNAALDH1A1KDM4EPOLB | |
| SCHEMBL28144325 | 0.70 | ADRB2 (0.55) | SMN1; SMN2LMNACA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922362-A | 1,3, 4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社钟根堂 | 2018-04-17 | — | — | CN | disclosed |