Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 14/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 14/20 | 0.51 |
| ▸ | EIF4E | P06730 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28859698 | 0.85 | MKNK1 (0.66) | ALDH1A1TNKSMKNK1MKNK2EIF4E | |
| SCHEMBL28216628 | 0.84 | MKNK1 (0.66) | ALDH1A1TNKSMKNK1MKNK2EIF4E | |
| SCHEMBL28217093 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TNKSMKNK1MKNK2EIF4E | |
| SCHEMBL16380067 | 0.80 | PAK4 (0.48) | ALDH1A1MKNK1MKNK2EIF4ECA12 | |
| SCHEMBL18325872 | 0.80 | PAK4 (0.47) | ALDH1A1MKNK1MKNK2EIF4EKCNH2 | |
| SCHEMBL28234722 | 0.75 | MKNK1 (0.52) | ALDH1A1MKNK1MKNK2 | |
| SCHEMBL980203 | 0.73 | TNKS (0.66) | ALDH1A1TNKSCA12CA1CA2 | |
| SCHEMBL16385826 | 0.72 | HPGD (0.54) | ALDH1A1TNKSMKNK1MKNK2EIF4E | |
| SCHEMBL3694272 | 0.72 | NPC1 (0.67) | ALDH1A1TNKSCA12CA1CA2 | |
| SCHEMBL21166248 | 0.72 | SLC6A7 (0.57) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |