SCHEMBL28217326

SCHEMBL28217326

CC(COOC(C)(C)C)c1ccccc1.C[CH]C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.44
TAAR1 Q96RJ0 3/20 0.41
AOC3 Q16853 2/20 0.38
TRPA1 O75762 6/20 0.37
CACNA1F O60840 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
ADRA2B P18089 1/20 0.35
CHRM3 P20309 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
OPRK1 P41145 1/20 0.35
CACNA1D Q01668 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 1/20 0.35
CACNA1S Q13698 1/20 0.35
CACNA1C Q13936 1/20 0.35
SCN5A Q14524 1/20 0.35
CASR P41180 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1077953 0.95 RIPK1 (0.48) RIPK1TAAR1AOC3TRPA1CACNA1F
SCHEMBL361156 0.85 RIPK1 (0.35) RIPK1TAAR1
SCHEMBL449071 0.82 RIPK1 (0.35) RIPK1TAAR1CACNA1FCHRM2CHRM1
SCHEMBL4084906 0.80 IDO1 (0.37) RIPK1CASR
SCHEMBL3632312 0.79 TAAR1 (0.56) RIPK1TAAR1AOC3TRPA1HRH1
SCHEMBL9784725 0.79 ALDH1A1 (0.44)
SCHEMBL17710275 0.79 MAPK1 (0.49) RIPK1TAAR1CACNA1FCHRM2CHRM1
SCHEMBL48451 0.78 TSHR (0.35) RIPK1
SCHEMBL20572715 0.78 CYP1A2 (0.43) RIPK1TAAR1CACNA1FCHRM2CHRM1
SCHEMBL4074326 0.78 HDAC4 (0.37) RIPK1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104284935-B The ethene polymers conducting paints prepared using polybutadiene cross linking co-agents 陶氏环球技术有限责任公司 2018-05-18 CN disclosed