SCHEMBL28217752

SCHEMBL28217752

Oc1ccc(S(c2ccccc2)(c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA9 Q16790 3/20 0.53
CA3 P07451 2/20 0.53
CA4 P22748 2/20 0.53
CA14 Q9ULX7 2/20 0.53
GLA P06280 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ESR1 P03372 5/20 0.50
ESR2 Q92731 3/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
LMNA P02545 2/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GMNN O75496 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18309904 1.00 CA12 (0.53) CA12CA1CA2CA9CA3
SCHEMBL8369054 0.88 CA2 (0.57) CA12CA1CA2CA9CA3
SCHEMBL18401049 0.85 HTR6 (0.50) CA12CA1CA2CA9CA3
SCHEMBL21017486 0.85 HTR6 (0.50) CA12CA1CA2CA9CA3
SCHEMBL3259521 0.82 HTR6 (0.53) CA12CA1CA2CA9CA3
SCHEMBL24593473 0.79 ENPP2 (0.52) CA12CA1CA2CA9CA3
SCHEMBL14647641 0.79 ENPP2 (0.52) CA12CA1CA2CA9CA3
SCHEMBL312518 0.79 HTR6 (0.70) CA12CA1CA2CA9ESR1
SCHEMBL21581122 0.79 CA12 (0.48) CA12CA1CA2CA9CA3
SCHEMBL7937451 0.79 HTR6 (0.70) CA12CA1CA2CA9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108117645-A The poly- fragrant acid imide manufacturing method of one kind and its process units 梅雪 2018-06-05 CN claimed
CN-108117645-A The poly- fragrant acid imide manufacturing method of one kind and its process units 梅雪 2018-06-05 CN disclosed