SCHEMBL28217811

SCHEMBL28217811

C[Si](C)(C)c1ccccc1F.[LiH]

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.42
NFE2L2 Q16236 8/20 0.40
IDO1 P14902 2/20 0.33
NOTUM Q6P988 1/20 0.33
MCL1 Q07820 1/20 0.33
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932025 0.97 ACHE (0.43) ACHENFE2L2IDO1NOTUMMCL1
Boric Acid SCHEMBL29277889 0.88 ACHE (0.37) ACHENFE2L2IDO1GAACES2
Phosphoric Acid SCHEMBL29277885 0.84 GAA (0.38) ACHENFE2L2NPC1GAARAB9A
SCHEMBL1880902 0.83 IDO1 (0.41) ACHEIDO1NPC1RAB9ASMN1; SMN2
SCHEMBL29726936 0.83 IDO1 (0.41) ACHEIDO1NPC1RAB9ASMN1; SMN2
SCHEMBL15091550 0.79 ACHE (0.42) ACHENFE2L2NOTUMNPC1GAA
SCHEMBL18692020 0.77 ACHE (0.46) ACHENFE2L2NOTUMNPC1GAA
SCHEMBL28071870 0.77 ACHE (0.40) ACHENFE2L2NOTUMNPC1GAA
SCHEMBL713563 0.77 CES2 (0.38) ACHEIDO1CES2CES1
SCHEMBL13621359 0.75 ACHE (0.39) ACHENFE2L2IDO1NOTUMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108084013-B Synthetic method of 3-bromo-2-fluorobenzoic acid 蓬莱市前卫化工有限公司 2020-09-01 CN claimed
CN-108084013-A A kind of synthetic method of the bromo- 2- fluobenzoic acids of 3- 上海晋鲁医药科技有限公司 2018-05-29 CN claimed
CN-108084013-B Synthetic method of 3-bromo-2-fluorobenzoic acid 蓬莱市前卫化工有限公司 2020-09-01 CN disclosed
CN-108084013-B Synthetic method of 3-bromo-2-fluorobenzoic acid 蓬莱市前卫化工有限公司 2020-09-01 CN disclosed
CN-108084013-A A kind of synthetic method of the bromo- 2- fluobenzoic acids of 3- 上海晋鲁医药科技有限公司 2018-05-29 CN disclosed