Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498970 | 0.84 | MEN1 (0.46) | MEN1KMT2ANOTUM | |
| SCHEMBL22290559 | 0.78 | KDM4E (0.41) | ALDH1A1LMNA | |
| SCHEMBL13850517 | 0.77 | LMNA (0.43) | KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL25258396 | 0.77 | KDM4E (0.41) | ALDH1A1LMNA | |
| SCHEMBL16543478 | 0.74 | BAZ2B (0.39) | MEN1KMT2ANOTUMALDH1A1LMNA | |
| SCHEMBL16543479 | 0.74 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL28218784 | 0.72 | KDM5A (0.44) | — | |
| SCHEMBL24035867 | 0.70 | NOTUM (0.46) | MEN1KMT2ANOTUMALDH1A1LMNA | |
| SCHEMBL22290701 | 0.68 | GABRG2 (0.34) | — | |
| SCHEMBL24035865 | 0.66 | NOTUM (0.45) | MEN1KMT2ANOTUMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209467-B | Imidazopyrrolidinone derivatives and their use in the treatment of disease | 诺华股份有限公司 | 2018-06-08 | — | — | CN | disclosed |