SCHEMBL28219127

SCHEMBL28219127

C=Cc1ccc(C=Nc2ccccc2N)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.43
RAB9A P51151 4/20 0.43
NPC1 O15118 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 9/20 0.41
KDM4E B2RXH2 7/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
USP2 O75604 4/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 5/20 0.41
HPGD P15428 4/20 0.41
LMNA P02545 4/20 0.41
HTT P42858 3/20 0.40
GLA P06280 1/20 0.40
PKM P14618 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28599218 0.84 KDM4E (0.55) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL17973873 0.84 KDM4E (0.55) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL28599893 0.78 CA12 (0.46) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL5131925 0.78 MEN1 (0.49) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL5131927 0.78 MEN1 (0.49) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL11423398 0.76 DHODH (0.64) GAARAB9ANPC1ALDH1A1KDM4E
SCHEMBL11423396 0.76 DHODH (0.64) GAARAB9ANPC1ALDH1A1KDM4E
SCHEMBL10057524 0.72 NPC1 (0.50) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL8405288 0.72 ALDH1A1 (0.58) GAARAB9ANPC1L3MBTL1ALDH1A1
SCHEMBL8405291 0.72 ALDH1A1 (0.58) GAARAB9ANPC1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108084448-B Cadmium polymerization complex containing 4, 5-dimethyl-1, 2-phenylenediamine derivative and preparation method and application thereof 湘潭大学 2020-10-30 CN claimed
CN-108084448-B Cadmium polymerization complex containing 4, 5-dimethyl-1, 2-phenylenediamine derivative and preparation method and application thereof 湘潭大学 2020-10-30 CN disclosed
CN-108084448-A One kind -1,2- of dimethyl containing 4,5- phenylenediamine derivatives close cadmium oligometric comples and preparation method and purposes 湘潭大学 2018-05-29 CN disclosed