Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551933 | 0.81 | MAOB (0.46) | MAOAMAOBOPRL1MAPT | |
| SCHEMBL28544407 | 0.78 | MAOB (0.46) | MAOAMAOB | |
| SCHEMBL12821714 | 0.75 | MAOB (0.56) | MAOAMAOBOPRL1 | |
| SCHEMBL4076627 | 0.75 | OPRL1 (0.45) | MAOAMAOBALDH1A1TSHRCYP3A4 | |
| SCHEMBL28219677 | 0.70 | MAOA (0.44) | MAOAMAOBHRH3 | |
| SCHEMBL4048459 | 0.69 | OPRL1 (0.41) | MAOAMAOBOPRL1HRH3 | |
| SCHEMBL205962 | 0.69 | MAOA (0.61) | MAOAMAOBOPRL1 | |
| SCHEMBL1509619 | 0.69 | ALDH1A1 (0.65) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL4047850 | 0.68 | OPRL1 (0.40) | MAOAMAOBOPRL1 | |
| SCHEMBL29577686 | 0.68 | ALDH1A1 (0.56) | ALDH1A1TSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-108135175-A | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2018-06-08 | — | — | CN | disclosed |