Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | AQP1 | P29972 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349239 | 0.85 | MAOB (0.61) | MAOBMAOAKDM1ARCOR1LOXL2 | |
| SCHEMBL28551933 | 0.82 | MAOB (0.46) | MAOBMAOAKDM1ATAAR1IDO1 | |
| SCHEMBL1823777 | 0.81 | MAOA (0.52) | MAOBMAOAKDM1ARCOR1LOXL2 | |
| Hydrochloric Acid SCHEMBL3969767 | 0.79 | MAOB (0.50) | MAOBMAOAKDM1ARCOR1LOXL2 | |
| SCHEMBL12821714 | 0.79 | MAOB (0.56) | MAOBMAOAKDM1ATAAR1IDO1 | |
| SCHEMBL4118593 | 0.78 | AQP1 (0.41) | MAOBMAOAKDM1ARCOR1LOXL2 | |
| SCHEMBL14409705 | 0.77 | TAAR1 (0.36) | MAOBMAOAKDM1ARCOR1LOXL2 | |
| SCHEMBL28536932 | 0.72 | TAAR1 (0.40) | MAOBMAOAKDM1ARCOR1TAAR1 | |
| SCHEMBL29218585 | 0.72 | MAOB (0.48) | MAOBMAOAKDM1ARCOR1 | |
| SCHEMBL23827531 | 0.70 | MAOA (0.44) | MAOBMAOAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |