Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544407 | 0.79 | MAOB (0.46) | MAOBMAOATAAR1KDM1AIDO1 | |
| SCHEMBL28551933 | 0.79 | MAOB (0.46) | MAOBMAOATAAR1KDM1AOPRL1 | |
| SCHEMBL28219637 | 0.75 | MAOA (0.42) | MAOBMAOAOPRL1 | |
| SCHEMBL1318340 | 0.73 | MAOA (1.00) | MAOBMAOAKDM1AOPRL1 | |
| Biphenyl SCHEMBL27474545 | 0.73 | ALDH1A1 (0.56) | MAOBMAOATAAR1KDM1AOPRL1 | |
| Hydrochloric Acid SCHEMBL1318464 | 0.72 | MAOA (0.95) | MAOBMAOAKDM1AOPRL1 | |
| SCHEMBL23827531 | 0.71 | MAOA (0.44) | MAOBMAOAKDM1A | |
| SCHEMBL28219677 | 0.71 | MAOA (0.44) | MAOBMAOATAAR1KDM1AIDO1 | |
| SCHEMBL6430626 | 0.71 | AKT2 (0.46) | MAOBMAOATAAR1KDM1AIDO1 | |
| SCHEMBL433971 | 0.70 | MAOA (0.83) | MAOBMAOAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135632-A2 | METHODS OF TREATING A SUBJECT HAVING BEEN EXPOSED TO A CATASTROPHIC EVENT | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-10-04 | — | — | WO | claimed |