Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861208 | 0.84 | NAMPT (0.48) | XDHSLC22A12HTTLMNAMRGPRX4 | |
| SCHEMBL7572805 | 0.83 | BCL2 (0.40) | PTPN1PTPN2PTPN6TSHRLMNA | |
| SCHEMBL10595252 | 0.82 | LMNA (0.43) | PTPN1PTPN2PTPN6LMNAFFAR1 | |
| SCHEMBL23480907 | 0.80 | SLC22A12 (0.46) | XDHSLC22A12HTTMRGPRX4TRPM4 | |
| SCHEMBL394617 | 0.80 | XDH (0.46) | XDHSLC22A12HTTMRGPRX4TRPM4 | |
| SCHEMBL31084678 | 0.79 | XDH (0.45) | PTPN1XDHSLC22A12HTTMRGPRX4 | |
| SCHEMBL6772376 | 0.78 | TSHR (0.69) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| SCHEMBL8961442 | 0.78 | PTPN1 (0.65) | PTPN1PTPN2PTPN6TSHRHNF4A | |
| Bicarbonate SCHEMBL11600449 | 0.78 | LMNA (0.43) | LMNABCL2BCL2L1FFAR1 | |
| SCHEMBL6441850 | 0.77 | PTPN1 (0.62) | PTPN1PTPN2PTPN6TSHRHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106748935-B | A kind of method that S- substituted benzoic acid thioes derivatives are synthesized by Bunte salt | 南京理工大学 | 2018-06-12 | — | — | CN | disclosed |