Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | P4HB | P07237 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860238 | 0.79 | MET (0.47) | METNPC1TP53MAPTSMN1; SMN2 | |
| SCHEMBL2611069 | 0.77 | CCR1 (0.40) | METTP53MAPT | |
| Quinoline SCHEMBL28220135 | 0.77 | MET (0.46) | METNPC1TP53MAPTSMN1; SMN2 | |
| SCHEMBL13228790 | 0.72 | ALDH1A1 (0.38) | METNPC1TP53MAPTSMN1; SMN2 | |
| SCHEMBL13078796 | 0.69 | TYR (0.37) | METPIK3CAKDM4E | |
| SCHEMBL974878 | 0.68 | PIK3CA (0.43) | NPC1ALOX5APFEN1TP53MAPT | |
| SCHEMBL17071859 | 0.68 | IDO1 (0.50) | MAPTCYP3A4 | |
| SCHEMBL30411144 | 0.68 | IDO1 (0.50) | MAPTCYP3A4 | |
| SCHEMBL16154382 | 0.68 | IDO1 (0.50) | MAPTCYP3A4 | |
| SCHEMBL17071857 | 0.68 | IDO1 (0.50) | MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137547-A | It can be used as the heterocyclic compound of TNF α conditioning agent | 百时美施贵宝公司 | 2018-06-08 | — | — | CN | disclosed |