Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607475 | 0.82 | MAOA (0.57) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL28494617 | 0.82 | MAOA (0.57) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL455949 | 0.79 | MAOA (1.00) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL28953244 | 0.77 | MAOA (0.52) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL6679033 | 0.77 | MAOA (0.70) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL28400797 | 0.77 | MAOA (0.95) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL10964206 | 0.76 | GPR3 (0.56) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL29175203 | 0.76 | MAOA (0.67) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL11668050 | 0.75 | MAOA (0.59) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL28462683 | 0.75 | MAOA (0.48) | MAOAMAOBKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715612-A | SOMATOSTATIN MODULATORS AND USES THEREOF | 克林提克斯医药股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-108137547-A | It can be used as the heterocyclic compound of TNF α conditioning agent | 百时美施贵宝公司 | 2018-06-08 | — | — | CN | disclosed |