Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222211 | 0.80 | NNMT (0.40) | NNMTPARP1 | |
| Hydrochloric Acid SCHEMBL6810406 | 0.79 | NNMT (0.39) | NNMTPARP1 | |
| SCHEMBL15922616 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTAGBL2CFTR | |
| SCHEMBL15991473 | 0.76 | BACE1 (0.44) | SYKKCNH2SMN1; SMN2KDM4EMAPT | |
| SCHEMBL24301085 | 0.74 | NNMT (0.43) | SYKNNMTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL12828104 | 0.74 | CYP2A6 (0.33) | AGBL2 | |
| SCHEMBL26928475 | 0.73 | AGBL2 (0.50) | NNMTSMN1; SMN2KDM4EMAPTAGBL2 | |
| SCHEMBL3090048 | 0.72 | NOS3 (0.48) | SYKKCNH2NNMTMAPTPARP1 | |
| SCHEMBL9537673 | 0.71 | LRRK2 (0.42) | SYKKCNH2NNMTSMN1; SMN2KDM4E | |
| SCHEMBL2219734 | 0.71 | NNMT (0.46) | SYKNNMTSMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137513-A | Pyrimidine derivatives | ASKA 制药株式会社 | 2018-06-08 | — | — | CN | disclosed |