Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15922616 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTALDH1A1CFTR | |
| SCHEMBL25934216 | 0.81 | HTR1D (0.37) | ALDH1A1HTR1DHTR1BPOLB | |
| SCHEMBL3090048 | 0.79 | NOS3 (0.48) | NNMTMAPTIKBKBPOLBSYK | |
| SCHEMBL24301085 | 0.77 | NNMT (0.43) | NNMTSMN1; SMN2KDM4EIKBKBALDH1A1 | |
| SCHEMBL2219734 | 0.77 | NNMT (0.46) | NNMTSMN1; SMN2LMNASYK | |
| SCHEMBL4049472 | 0.76 | L3MBTL1 (0.42) | LRRK2NNMTKDM4EKMT2AL3MBTL1 | |
| SCHEMBL3129841 | 0.76 | BACE1 (0.44) | NNMTKDM4EALDH1A1KMT2A | |
| SCHEMBL26928475 | 0.76 | AGBL2 (0.50) | NNMTSMN1; SMN2KDM4EMAPTPOLB | |
| Hydrochloric Acid SCHEMBL28641941 | 0.76 | NNMT (0.44) | NNMTSMN1; SMN2LMNASYK | |
| SCHEMBL29621570 | 0.76 | BACE1 (0.44) | NNMTKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373933-A1 | SMALL MOLECULE COMPOUND SERVING AS JAK KINASE INHIBITOR AND USE THEREOF | TECHNODERMA MEDICINES INC (CN) | 2023-11-23 | — | — | US | disclosed |
| EP-4227298-A1 | SMALL MOLECULE COMPOUND SERVING AS JAK KINASE INHIBITOR AND USE THEREOF | Technoderma Medicines Inc. (CN) | 2023-08-16 | — | — | EP | disclosed |
| EP-0535152-A1 | BIS-BENZO OR BENZOPYRIDO CYCLO HEPTA PIPERIDENE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS AND COMPOSITIONS. | SCHERING CORP (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000293-A1 | BIS-BENZO OR BENZOPYRIDO CYCLO HEPTA PIPERIDENE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373933-A1 | SMALL MOLECULE COMPOUND SERVING AS JAK KINASE INHIBITOR AND USE THEREOF | JAK1, TYK2, JAK2 | LRRK2 302/4885NNMT 1128/4885SMN1; SMN2 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.