SCHEMBL28223003

SCHEMBL28223003

CC1(C)c2ccccc2-c2cc(O)c(Br)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
PDK2 Q15119 5/20 0.38
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AKR1C1 Q04828 1/20 0.36
PRMT1 Q99873 1/20 0.35
DRD1 P21728 5/20 0.34
DRD2 P14416 2/20 0.34
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
SLC6A2 P23975 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20932322 0.93 ESR1 (0.39) ESR1ESR2PDK2CASP3RAB9A
SCHEMBL29705959 0.87 ALOX15 (0.34) CASP3RAB9AATMNPSR1SENP8
SCHEMBL20209377 0.87 ALOX15 (0.34) CASP3RAB9AATMNPSR1SENP8
SCHEMBL20931872 0.85 ESR1 (0.43) ESR1ESR2PDK2CASP3RAB9A
SCHEMBL21551950 0.85 PDK2 (0.39) ESR1ESR2PDK2AKR1C1DRD1
SCHEMBL546245 0.81 PDK2 (0.39) ESR1ESR2PDK2CASP3RAB9A
SCHEMBL23076421 0.79 ALDH1A1 (0.35) PDK2RAB9ADRD1DRD2ADRA2A
SCHEMBL23870792 0.79 PDK2 (0.35) PDK2DRD1DRD2ADRA2AADRA2B
SCHEMBL22920726 0.79 PGR (0.38) PDK2DRD1DRD2ADRA2AADRA2B
SCHEMBL28222286 0.79 PDK2 (0.39) ESR1ESR2PDK2CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108203428-A A kind of compound and its application using carbazole as core 江苏三月光电科技有限公司 2018-06-26 CN disclosed
CN-108203427-A It is a kind of using carbazole as the compound of core and its application on organic electroluminescence device 江苏三月光电科技有限公司 2018-06-26 CN disclosed