Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28235212 | 0.98 | LMNA (0.36) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL29179325 | 0.88 | CYP3A4 (0.42) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL28126462 | 0.79 | CHRM5 (0.40) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| SCHEMBL2122127 | 0.77 | TSHR (0.32) | MEN1KMT2ATSHR | |
| SCHEMBL28712979 | 0.77 | TSHR (0.32) | MEN1KMT2ATSHR | |
| SCHEMBL8732915 | 0.75 | ALDH1A1 (0.38) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2121874 | 0.74 | — | — | |
| SCHEMBL3829004 | 0.74 | TSHR (0.43) | CYP3A4MAPTLMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28486149 | 0.74 | CHRM5 (0.39) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL29050268 | 0.73 | SMN1; SMN2 (0.46) | CYP3A4SLC5A7CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909006-B | Green high-efficiency conversion extraction method of resveratrol in giant knotweed rhizome | 湖北工业大学 | 2022-07-05 | — | — | CN | claimed |
| CN-113663361-A | Method for extracting polyphenol compounds in olive leaves by using eutectic solvent | 河南工业大学 | 2021-11-19 | — | — | CN | claimed |
| CN-112544712-A | Lentinan soluble bean for improving intestinal immunity of children by diet and preparation method thereof | 钟祥兴利食品股份有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-111909006-A | Green high-efficiency conversion extraction method of resveratrol in polygonum cuspidatum | 湖北工业大学 | 2020-11-10 | — | — | CN | claimed |
| CN-110981274-A | Silicate concrete corrosion resistance additive and preparation method thereof | 李可昕 | 2020-04-10 | — | — | CN | claimed |
| CN-117925750-A | Method for extracting houttuynia cordata polysaccharide | 浙江工业大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117821527-A | Method for synthesizing vanillic acid | 江苏大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-117476126-B | Propolis flavone extraction method for targeted preparation of uric acid-reducing activity and application | 中国农业科学院蜜蜂研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-117567661-A | Eutectic solvent extraction method of tremella aurantialba polysaccharide | 成都农业科技中心 | 2024-02-20 | — | — | CN | disclosed |
| CN-117476126-A | Propolis flavone extraction method for targeted preparation of uric acid-reducing activity and application | 中国农业科学院蜜蜂研究所 | 2024-01-30 | — | — | CN | disclosed |
| CN-115252659-B | Method for extracting polyphenol compounds from torreya grandis aril by using enzymolysis coupled ultrasonic auxiliary eutectic solvent | 浙江工业大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-115708845-B | Extraction method of rehmannia root extract and application of rehmannia root extract in preparation of anti-inflammatory drugs | 河南省纳普生物技术有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-108246325-B | Preparation method and application of vanadyl phosphate catalyst | 中国科学院过程工程研究所 | 2020-09-11 | — | — | CN | disclosed |
| CN-111450139-A | Eutectic solvent and method for preparing spina gleditsiae total flavonoids by using same | 山东省分析测试中心 | 2020-07-28 | — | — | CN | disclosed |
| CN-111450139-A | Eutectic solvent and method for preparing spina gleditsiae total flavonoids by using same | 山东省分析测试中心 | 2020-07-28 | — | — | CN | disclosed |
| CN-111039912-A | Method for extracting flavonoid compounds in wild rice by using deep eutectic solvent | 中国农业科学院烟草研究所 | 2020-04-21 | — | — | CN | disclosed |
| CN-110981274-A | Silicate concrete corrosion resistance additive and preparation method thereof | 李可昕 | 2020-04-10 | — | — | CN | disclosed |
| CN-108354960-A | A kind of method of flavonoid glycoside compound in extraction Herba Epimedii | 沈阳药科大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-108246325-A | A kind of preparation method and its usage of vanadyl phosphate catalyst | 中国科学院过程工程研究所 | 2018-07-06 | — | — | CN | disclosed |
| CN-108088943-A | Extractant-eutectic is dissolved in the application during effective component of chinese medicine measures | 沈阳药科大学 | 2018-05-29 | — | — | CN | disclosed |