Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860721 | 0.85 | LOXL2 (0.40) | KDM4ESMN1; SMN2LOXL2NOS3NOS1 | |
| SCHEMBL8028836 | 0.80 | ESR1 (0.43) | KDM4EESR1ESR2ABAT | |
| SCHEMBL28468309 | 0.80 | TGM2 (0.42) | SMN1; SMN2 | |
| SCHEMBL28469749 | 0.78 | BRD4 (0.50) | SMN1; SMN2THRB | |
| SCHEMBL7252884 | 0.78 | HDAC3 (0.42) | SMN1; SMN2HDAC3HDAC6 | |
| SCHEMBL28470051 | 0.75 | CYP1A2 (0.39) | SMN1; SMN2 | |
| SCHEMBL8040582 | 0.75 | MAPT (0.48) | KDM4E | |
| SCHEMBL8028848 | 0.74 | MAPT (0.38) | KDM4ELOXL2NOS3NOS1 | |
| SCHEMBL8042292 | 0.74 | TGM2 (0.45) | — | |
| SCHEMBL8279092 | 0.73 | KDM4E (0.47) | KDM4ESMN1; SMN2LOXL2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358831-A | A kind of polysubstituted carbazole derivates and preparation method thereof | 山东师范大学 | 2018-08-03 | — | — | CN | disclosed |