Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028836 | 0.84 | ESR1 (0.43) | BRD4TSHRALOX15GAASLC6A3 | |
| SCHEMBL28468309 | 0.84 | TGM2 (0.42) | POLBHTTSMN1; SMN2LMNACNR1 | |
| SCHEMBL7252884 | 0.82 | HDAC3 (0.42) | HDAC4HDAC7HDAC5POLBGAA | |
| SCHEMBL28900487 | 0.80 | MEN1 (0.41) | POLBNPC1GAAHTTRAB9A | |
| SCHEMBL28470051 | 0.79 | CYP1A2 (0.39) | TSHRNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL8040582 | 0.79 | MAPT (0.48) | ALOX15NPC1RAB9ACYP3A4MEN1 | |
| SCHEMBL28224852 | 0.78 | KDM4E (0.39) | SMN1; SMN2THRB | |
| SCHEMBL8028848 | 0.78 | MAPT (0.38) | TSHRGAAHTT | |
| SCHEMBL8042292 | 0.78 | TGM2 (0.45) | CYP1A2 | |
| SCHEMBL38660598 | 0.77 | BRD4 (0.57) | BRD4HDAC4HDAC7HDAC5FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358831-B | Polysubstituted carbazole derivative and preparation method thereof | 山东师范大学 | 2020-09-29 | — | — | CN | disclosed |