SCHEMBL28224970

SCHEMBL28224970

Cc1cc(-c2ccc3c(c2-c2cc(C)c(N)c(C)c2)Cc2ccccc2-3)cc(C)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.43
ALDH1A1 P00352 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
PNMT P11086 1/20 0.40
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
ACHE P22303 7/20 0.37
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
BCHE P06276 1/20 0.35
HTR7 P34969 2/20 0.34
HTR2B P41595 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20640814 0.86 PNMT (0.46) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL28291449 0.85 PGR (0.43) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL31030083 0.85 PGR (0.43) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL7919926 0.83 PGR (0.44) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL31046749 0.83 PGR (0.44) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL10344111 0.83 PGR (0.41) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL28312235 0.82 PNMT (0.43) PGRALDH1A1NPC1RAB9ASMN1; SMN2
Benzene SCHEMBL28224971 0.82 PGR (0.43) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL28312207 0.82 EGFR (0.41) PGRALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL29800244 0.80 PGR (0.41) PGRALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110114384-A Curable compositions 3M创新有限公司 2019-08-09 CN disclosed
CN-105612600-B Element processing laminated body, the manufacturing method of element processing laminated body and the manufacturing method using its thin component 东丽株式会社 2018-06-08 CN disclosed