SCHEMBL28225548

SCHEMBL28225548

CC1=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1[Si](C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RXRB P28702 2/20 0.32
RXRA P19793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16829502 0.82
Hydrochloric Acid SCHEMBL6454486 0.82
SCHEMBL5859272 0.82 RXRB (0.34) RXRBRXRA
SCHEMBL16829541 0.81 PTGS2 (0.33)
SCHEMBL29036028 0.81 HTR1A (0.33)
SCHEMBL28050148 0.81 RXRB (0.33) RXRBRXRA
SCHEMBL16393905 0.81 RXRB (0.33) RXRBRXRA
SCHEMBL28198736 0.81 RXRB (0.33) RXRBRXRA
SCHEMBL16685014 0.80 RXRB (0.31) RXRBRXRA
Hydrochloric Acid SCHEMBL16394004 0.80 RXRB (0.33) RXRBRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377904-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-07-10 CN disclosed