Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076607 | 0.75 | HTR1A (0.58) | HTR1ASLC6A4 | |
| SCHEMBL3577962 | 0.75 | RYR2 (0.49) | HTR1ASLC6A4RYR2 | |
| SCHEMBL3587135 | 0.73 | PIK3CG (0.52) | HTR1ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL28076704 | 0.73 | GAA (0.56) | HTR1ASLC6A4MEN1KMT2AGAA | |
| SCHEMBL3582211 | 0.72 | EPHX2 (0.55) | MEN1KMT2ARYR2 | |
| SCHEMBL28076624 | 0.72 | HTR1A (0.52) | HTR1ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL28225671 | 0.72 | HTR1A (0.45) | HTR1ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL3586208 | 0.72 | MEN1 (0.43) | HTR1ASLC6A4MEN1POLBKMT2A | |
| SCHEMBL28076582 | 0.71 | CYP2D6 (0.55) | HTR1ASLC6A4RYR2GAA | |
| SCHEMBL3574540 | 0.71 | MTNR1A (0.44) | HTR1ASLC6A4MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646331-B | Piperidine compounds, the medical composition and its use containing the compound | 爱思开生物制药株式会社 | 2018-07-03 | — | — | CN | disclosed |