Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076582 | 0.91 | CYP2D6 (0.55) | GAADRD4HTR1ASLC6A4MAPT | |
| SCHEMBL28076624 | 0.85 | HTR1A (0.52) | GAADRD4HTR1ASLC6A4MEN1 | |
| SCHEMBL28830757 | 0.79 | TSHR (0.60) | GAADRD4MEN1KMT2ACYP2D6 | |
| SCHEMBL28830809 | 0.79 | DRD4 (0.62) | GAADRD4MEN1KMT2AMAPT | |
| SCHEMBL28076585 | 0.78 | DRD4 (0.58) | GAADRD4MEN1KMT2AMAPT | |
| SCHEMBL28076798 | 0.78 | HTR1A (0.55) | HTR1ASLC6A4CCR3 | |
| SCHEMBL28076611 | 0.78 | MAPT (0.48) | GAADRD4HTR1ASLC6A4MEN1 | |
| SCHEMBL28076708 | 0.78 | ADRA1A (0.49) | GAADRD4HTR1ASLC6A4MEN1 | |
| SCHEMBL8733371 | 0.77 | SLC18A3 (0.61) | GAADRD4MEN1KMT2ATDP1 | |
| SCHEMBL28076620 | 0.75 | HTR1A (0.46) | GAADRD4HTR1ASLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | claimed |