Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 10/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16395913 | 0.85 | HTR6 (0.40) | HTR6NAMPTCCR6SLC40A1KAT6A | |
| SCHEMBL16395932 | 0.82 | GAA (0.44) | HTR6NAMPTCCR6CHRM2CHRM1 | |
| SCHEMBL28226237 | 0.80 | SLC40A1 (0.46) | HTR6NAMPTSLC40A1KAT6A | |
| SCHEMBL28226231 | 0.79 | KAT6A (0.44) | HTR6NAMPTSLC40A1KAT6AHDAC3 | |
| SCHEMBL13981836 | 0.75 | CCR6 (0.52) | CCR6CHRM2CHRM1CHRM3 | |
| SCHEMBL22954096 | 0.72 | KAT6A (0.53) | HTR6NAMPTSLC40A1KAT6A | |
| SCHEMBL26936759 | 0.72 | SIRT2 (0.46) | KAT6A | |
| SCHEMBL22545577 | 0.71 | HDAC8 (0.41) | NAMPTSLC40A1KAT6AHDAC3HDAC4 | |
| SCHEMBL9778961 | 0.71 | PTGES2 (0.52) | HTR6NAMPTSLC40A1KAT6AHDAC3 | |
| SCHEMBL19754925 | 0.71 | NAMPT (0.51) | HTR6NAMPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-B | Hete rocyclic derivatives and application thereof | 株式会社C&C新药研究所 | 2018-08-17 | — | — | CN | disclosed |