Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25959894 | 0.84 | TOP1 (0.43) | SIRT2MTNR1AMTNR1BADRB2HTR1D | |
| SCHEMBL2967940 | 0.81 | TRIM24 (0.55) | SIRT2TRIM24NR1H4KAT6AFOS | |
| SCHEMBL5532468 | 0.80 | TP53 (0.53) | POLBMAPTHPGDKMT2AMAPK1 | |
| SCHEMBL9647573 | 0.77 | TRIM24 (0.49) | SIRT2TRIM24NR1H4KAT6AFOS | |
| SCHEMBL5786398 | 0.74 | MAPK1 (0.64) | TRIM24MTNR1AMTNR1BKMT2ATSHR | |
| SCHEMBL3723068 | 0.74 | ADRB2 (0.59) | TRIM24ADRB2MAPTKMT2A | |
| SCHEMBL8050864 | 0.74 | TRIM24 (0.47) | SIRT2TRIM24NR1H4KAT6AFOS | |
| SCHEMBL14878920 | 0.74 | MAPK1 (0.37) | KMT2ATSHRMAPK1 | |
| SCHEMBL8048490 | 0.74 | TRIM24 (0.47) | SIRT2TRIM24NR1H4KAT6AFOS | |
| SCHEMBL14314265 | 0.74 | RAB9A (0.40) | MAPTKMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |