Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860936 | 0.87 | DYRK1A (0.59) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28226338 | 0.84 | CASP3 (0.52) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28227094 | 0.84 | HTT (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28226336 | 0.84 | CASP3 (0.54) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28226387 | 0.84 | CASP3 (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28226361 | 0.84 | MAPT (0.49) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28227100 | 0.83 | KDM4E (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28227108 | 0.83 | CASP3 (0.62) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28226349 | 0.83 | USP2 (0.54) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28227101 | 0.83 | DYRK1A (0.62) | CASP3SENP8SENP7SENP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175408-B | Benzothiazole compound and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |