SCHEMBL28226604

SCHEMBL28226604

Oc1c(Cl)cc(C(F)(F)C(F)(c2cc(Cl)c(O)c(Cl)c2)C(F)(F)F)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.41
TSHR P16473 4/20 0.41
ALDH1A1 P00352 3/20 0.41
TTR P02766 2/20 0.41
CYP3A4 P08684 1/20 0.41
RECQL P46063 1/20 0.41
THRB P10828 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HIF1A Q16665 1/20 0.37
HPGD P15428 2/20 0.33
MAPK1 P28482 1/20 0.33
PLAU P00749 1/20 0.32
TXNRD1 Q16881 1/20 0.32
TXNRD3 Q86VQ6 1/20 0.32
TXNRD2 Q9NNW7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6844032 0.76 HSD17B10 (0.46) HSD17B10TSHRALDH1A1TTRCYP3A4
SCHEMBL5600053 0.75 ALDH1A1 (0.50) HSD17B10TSHRALDH1A1TTRCYP3A4
SCHEMBL542204 0.74 NR1H3 (0.44) HSD17B10TSHRALDH1A1TTRCYP3A4
SCHEMBL2833024 0.72 HSD17B10 (0.42) HSD17B10TSHRALDH1A1TTRCYP3A4
SCHEMBL299601 0.67 ALDH1A1 (0.46) TSHRALDH1A1CYP3A4CYP1A2CYP2C19
SCHEMBL5355959 0.67 ALDH1A1 (0.32) TSHRALDH1A1SMN1; SMN2PLAUAR
SCHEMBL16703686 0.67 NPSR1 (0.35) ALDH1A1HPGDPLAUNPSR1
SCHEMBL18094297 0.67 NPSR1 (0.35) ALDH1A1HPGDPLAUNPSR1
SCHEMBL7029201 0.66 MEN1 (0.38) HSD17B10TSHRALDH1A1TTRCYP3A4
SCHEMBL6321695 0.66 GABRA1 (0.52) HSD17B10TSHRALDH1A1TTRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108693707-A Black-colored photosensitive resin composition and the display device manufactured using it 东友精细化工有限公司 2018-10-23 CN disclosed
CN-104423169-B Alkali-soluble resin, photosensitive resin composition, color filter and method for producing same, and liquid crystal display device 奇美实业股份有限公司 2018-07-13 CN disclosed